Oral Methylthioadenosine Administration Attenuates Fibrosis and Chronic Liver Disease Progression in Mdr2−/− Mice
Figure 5
Effect of MTA on the expression of inflammatory cytokines and iNOS in Mdr2−/− mouse liver.
mRNA levels of TNFα (A), IL6 (B), iNOS (C), Mcp-1 (D), TGFβ1 (E) and TGFβ2 (F) were measured in the liver of Mdr2+/+, control Mdr2−/−, and MTA-treated Mdr2−/− mice. *P<0.05 vs Mdr2+/+ mice, #P<0.05 vs untreated Mdr2−/− mice.