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Portrait of a Pathogen: The Mycobacterium tuberculosis Proteome In Vivo

Figure 1

Representative photomicrographs of A) day 30, B) day 90 post-infection guinea pig lungs, and C) uninfected guinea pig lungs.

Guinea pigs were aerosolized with a low dose infection of virulent Mtb (H37Rv). Tissues were stained (H&E) to demonstrate differences in granulomas based on size (primary granuloma, marked with the letter P) and the absence (secondary granuloma, marked with the letter S) of a necrotic core. Bars are 200 µm.

Figure 1

doi: https://doi.org/10.1371/journal.pone.0013938.g001