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Ricin Toxicokinetics and Its Sensitive Detection in Mouse Sera or Feces Using Immuno-PCR

Figure 4

Neutralization of ricin with polyclonal ricin antibodies.

Survival percentage of mice dosed iv (A) or ig (B) with ricin were plotted over 160 h post-intoxication. Goat anti-ricin antibodies were introduced iv either prior-to or post-intoxication at indicated times. PBS was injected into mice as no treatment control. Comparison of survival curves with log rank test yielded statistical significance of p<0.001 and p<0.0144 for A and B respectively.

Figure 4

doi: https://doi.org/10.1371/journal.pone.0012858.g004