High Viral Fitness during Acute HIV-1 Infection
Figure 6
Clinical and experimental data obtained for PHAEDRA subjects.
Shown are clinical and experimental data obtained for PHAEDRA subjects from which virus was successfully isolated and subsequently tested using the real time PCR assay. Indicated by the column headings are the subject identification code, seroconversion status at Baseline (‘+’ indicates subject had seroconverted, ‘-’ indicates subject was seronegative), and the phase of the PHAEDRA study at which the relevant sample was collected. The time (in weeks) post Baseline that the sample was collected, coincident VL and CD4+ T cell counts, and the sample type from which virus was successfully isolated are shown. The viral fitness scores calculated using DNA production measured at 96 h post-infection ex vivo, and at the final time-point analysed (110 h post-infection), are shown for each isolate.