Comprehensive Behavioral Analysis of Calcium/Calmodulin-Dependent Protein Kinase IV Knockout Mice
Figure 2
Anxiety-like behaviors in CaMKIV KO mice.
(A–F) Light/dark transition test: distance traveled in the light/dark compartments (A, E), time spent in the light compartment (B, F), latency to enter the light compartment (C), and number of light/dark transitions (D) were recorded. (G–L) Elevated plus maze: distance traveled (G), number of arm entries (H), percentage of time spent on open arms (I), percentage of entries into the open arms (J), percentage of time spent in the closed arms (K), and time spent in the center area (L) were recorded. (M, N) Open field test: total distance traveled (M) and time spent in the center of the compartment (N) were recorded. The p values indicate genotype effect in two-way ANOVA (A–D, G–L) and two-way repeated measures ANOVA (E, F, M, N).