Human Guanylate Binding Proteins Potentiate the Anti-Chlamydia Effects of Interferon-γ
Figure 7
hGBP1 potentiates the anti-chlamydial effects of IFN-γ.
Cell overexpressing myc-hGBP1 (A-C) or myc-hGBP D148N (D-F) were treated with a sub-inhibitory concentration (0.05 ng/ml) of IFN-γ at the time of infection with Ctr serovar L2 at MOI = 1 and processed for microscopy at 24 h p.i. White arrows indicate inclusions within transfected cells. Scale bar = 50 µm.