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Working Memory Cells' Behavior May Be Explained by Cross-Regional Networks with Synaptic Facilitation

Figure 10

Raster plots of 10 trials (left) for an excitatory (A) and an inhibitory (B) unit from the 4-population 2000 unit spiking network.

Note that different pattern types occur on different trials. Figures A and B (right) show an expanded version of 4 of the 10 trials from both units to highlight different patterns exhibited. From top to bottom of the expanded trials, the excitatory unit shows a decaying rate, nonresponsive, increasing rate, and persistent stable firing rate pattern, and the inhibitory unit shows decaying inhibition, stable inhibition, increasing rate excitation, and increasing inhibition. C) Rasters from 4 trials selected from a real neuron recorded from the prefrontal cortex during presentation of the same memorandum of the cross-modal task exhibiting stable persistent activation during the delay in the average PSTH. Although the cells exhibits stable persistent activation on average, on specific trials the cell exhibits the decaying rate activation pattern.

Figure 10

doi: https://doi.org/10.1371/journal.pone.0006399.g010