Optimization of Immunoglobulin Substitution Therapy by a Stochastic Immune Response Model
Figure 4
Simulation results for the time-averaged size of the bacteria population in the equilibrated system.
The time-averaged size of the bacteria population, , is computed as a function of the clearance rate
according to Eq. (68). The proliferation rate
and the carrying capacity
are kept fixed in the computations for different substitution therapies with frequencies
(black line),
(red line),
(green line), and
(blue line). It is clearly observed that the critical value of the clearance rate with
depends on the treatment frequency.