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Defective Peripheral Nerve Development Is Linked to Abnormal Architecture and Metabolic Activity of Adipose Tissue in Nscl-2 Mutant Mice

Figure 2

Reduced innervation of WAT in Nscl-2 deficient mice at different postnatal stages.

Paraffin sections of WAT from wild-type (A, C) and Nscl-2 −/− mice (B, D) at 2 (A, B) and 6 month (C, D) of age stained with an antibody against peripherin. Sections were taken from epididymal fat tissues. Note the reduction of peripherin positive nerves in Nscl-2 mutants. Scale bars 100 µm; in small pictures 15 µm.

Figure 2

doi: https://doi.org/10.1371/journal.pone.0005516.g002