Transcript-Specific Expression Profiles Derived from Sequence-Based Analysis of Standard Microarrays
Figure 3
Microarray and real-time RT-PCR transcript measurements of PLG and ABCA1 in two patient cohorts.
For the gene PLG, transcript PLMN_HUMAN was repressed in DD compared to LD controls, while Q5TEH_HUMAN showed no differential expression. Real-time RT-PCR measurements on the same tissues were in agreement with these findings. For gene ABCA1, transcript ABCA1_HUMAN was induced in DN compared to LD, and Q5VYS0_HUMAN was not regulated. Real-time RT-PCR measurement confirmed the induction of ABCA1_HUMAN. Q5VYS0_HUMAN was expressed at a too low level to be measured (value 0). Real-time data are normalized to the cohort with lower abundance.