Characterization of New Substrates Targeted By Yersinia Tyrosine Phosphatase YopH
Figure 4
Inhibition of different luciferase transcriptional reporters by YopH deletion mutants.
A, Activation of a luciferase reporter gene driven by NFAT/AP1. B, Activation of a NF-κB-driven luciferase reporter gene. C, Activation of a luciferase reporter gene driven by IL-2 promoter. In all cases, the data represent the mean±S.D. from triplicate determinations. *, p<0.05, **, p<0.005, ***, p<0.0005 as compared with pEF5 trasfected cells stimulated through TCR and CD28.