Lateral Transfer of a Lectin-Like Antifreeze Protein Gene in Fishes
Figure 1
Antifreeze protein - lectin structural comparisons.
(A) Rat mannose-binding protein structure (PDB code: 1KWT) and (B) Herring AFP structure (PDB code: 2PY2) showing the location of the 5th disulfide bridge that is peculiar to the type II AFPs. Secondary structure elements (red – helix; green – beta-strand; grey – loop) are numbered from the N terminus. Disulfide bonds are shown in yellow with the linkages of numbered cysteines indicated in brackets. LLR is the long loop region.