Conserved and Differential Effects of Dietary Energy Intake on the Hippocampal Transcriptomes of Females and Males
Figure 7
Hippocampi of male and female rats maintained on a HFG diet were compared to the hippocampi of rats maintained on a control (ad libitum) diet.
Genes that were significantly up-regulated (red) or down-regulated (green) were clustered into a Venn diagram. There were 8 significantly up-regulated and 6 significantly down-regulated genes in the hippocampi collected from HFG male rats compared to the genes from hippocampi collected from control (ad libitum) male rats. Hippocampi collected from HFG female rats showed 7 significantly up-regulated (red) and 7 significantly down-regulated (green) genes compared to the hippocampi collected from control (ad libitum) female rats. There were no significantly up-regulated or down-regulated common genes between male and female rats in this dietary group. Names of the significantly altered genes can be found in Table S1.