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Cannabinoids Reduce Markers of Inflammation and Fibrosis in Pancreatic Stellate Cells

Figure 1

Cannabinoid receptor 1 in human chronic pancreatitis tissues.

CB1 immunohistochemistry: staining of tubular complexes (A) but immunonegativity of infiltrating mononuclear cells (B); various staining intensities of intrapancreatic nerves (C&D); pancreatic stellate cells in areas of fibrosis (E) or isolated and cultured in vitro (F). Original magnification: x20 (A, B, D), x40 (C), x80 (F). Insets: negative controls. Lower insets (A): CB1 in normal pancreas.

Figure 1

doi: https://doi.org/10.1371/journal.pone.0001701.g001