Figures
The DB22-4 panels in Fig 1C [1] were erroneously used to represent the DB22-4 results in Fig 1D. An updated version of Fig 1 is provided here in which the DB22-4 panels in Fig 1D are replaced.
Original images underlying Fig 1C and 1D are provided in S1 and S2 Files.
The original underlying data to support all results in the article and Supporting Information files are available from the corresponding author, except for the original western blot images underlying the DB19-4 panel in Fig 1B, which are no longer available.
The authors apologize for the error in the published article.
A) C6/36 insect cells were infected by DENV-1, -2, -3 and -4 or uninfected (Mock). After fixation and permeabilization, mAbs were incubated with cells and binding was assessed by cellular ELISA. A490, optical density at 490 nm. (B) Identification of mAbs by Western blotting. C6/36 cells were infected with DENV-1 to -4 (D1, D2, D3 and D4) as viral antigens. Protein samples were dissolved in native sample buffer and fractionated by 10% SDS-PAGE. mAbs recognized E protein (53 kDa) of DENV. (C and D) mAbs recognized DENV-2 E protein and E-DI-II was determined by IFA, respectively. (E) Dissection of DENV-2 mAbs recognized E-DI-II or E-DIII by Western blot analysis. The DENV-2 recombinant E-DI-II-flag (36 kDa) and E-DIII-flag (17 kDa) fusion proteins were expressed in Escherichia coli. Protein extract was dissolved in denatured sample buffer and fractionated on 12% SDS-PAGE. 4G2, a cross-reactive mAb and 3H5, a DENV-2 serotype-specific mAb recognized D2-E-DI-II and D2-E-DIII, respectively. They were used as positive controls.
Reference
Citation: Li P-C, Liao M-Y, Cheng P-C, Liang J-J, Liu I-J, Chiu C-Y, et al. (2024) Correction: Development of a Humanized Antibody with High Therapeutic Potential against Dengue Virus Type 2. PLoS Negl Trop Dis 18(3): e0012031. https://doi.org/10.1371/journal.pntd.0012031
Published: March 13, 2024
Copyright: © 2024 Li et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.