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Discovery and Characterization of Novel Anti-schistosomal Properties of the Anti-anginal Drug, Perhexiline and Its Impact on Schistosoma mansoni Male and Female Reproductive Systems

Fig 9

Vitellarium alterations in adult female worms treated with PHX.

Representative confocal laser scanning microscope images of the vitellarium of adult female worms. S. mansoni worm couples were treated for 3 and 6 days with DMSO (A, E) or different doses of PHX (B-D, F-H) for 3 and 6 days as indicated and stained with carmine red. Scale bars = 25 μm in the low magnification panels and 2.5 μm in the high magnification insets indicated with yellow boxes.

Fig 9

doi: https://doi.org/10.1371/journal.pntd.0004928.g009