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Polymorphisms in Plasmodium vivax Circumsporozoite Protein (CSP) Influence Parasite Burden and Cytokine Balance in a Pre-Amazon Endemic Area from Brazil

Fig 2

Correlation between parasite density and the cytokine profile.

The x axis indicates Log Parasites/μL (A and B) or Log IL-6 (pg/mL) (C); the y axis indicates Log Interleukin 6 (pg/mL)(A), Log Interleukin 10 (pg/mL) (B) and (C). Each point represents the relative parasitaemia and cytokine responses of a single patient (A and B) or represents the relative IL-10 and IL-6 (C) responses of a single patient, n = 25 infected patients. The correlations were determined by Spearman’s correlation tests.

Fig 2

doi: https://doi.org/10.1371/journal.pntd.0004479.g002