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CT694 and pgp3 as Serological Tools for Monitoring Trachoma Programs

Figure 4

Antibody response in association with age.

Median responses are shown in median fluorescence intensity minus background (MFI-BG) for (A) pgp3 and (B) CT694 antibody positive responses by age ranges of less than 3 years old (n = 42), between 3 and less than 6 years old (n = 65), and 6 years or older (n = 52). Responses shown in red indicate PCR positivity. Responses in green are children with ocular pathology (shown only in the <3 age group). Children with both trachoma and PCR positivity are indicated by a red dot with a green border. For pgp3, children younger than three years of age had lower antibody responses than those who were between three and six and those who were older than six years of age (p<0.0001 and p = 0.0062, respectively). For CT694, children younger than three years of age had lower antibody responses than children between three and six (p = 0.0291) and children older than six (p = 0.0001).

Figure 4

doi: https://doi.org/10.1371/journal.pntd.0001873.g004