Synergistic Interactions between the NS3hel and E Proteins Contribute to the Virulence of Dengue Virus Type 1
Figure 7
Levels of immunity genes mRNAs in mice brains collected 8 days after infection.
The x axis shows DENV-1 variants and the y axis shows the relative levels of mRNAs detected with respect to murGAPDH mRNA. Data were analyzed by one-way ANOVA followed by Bonferroni correction and the values presented are the means ± SD of three different experiments. * p<0.05, ** p<0.01 and *** p<0.001. The significance bars correspond to comparisons between viruses that recover the virulent phenotype.