Synergistic Interactions between the NS3hel and E Proteins Contribute to the Virulence of Dengue Virus Type 1
Figure 3
(A) Representation of the full-length NS3 protein with the serine protease domain in red and the helicase domain in blue, with different shades of blue fused to represent the various subdomains. (B) Detailed view of amino acids 167–498, encompassing subdomains I and II of the helicase. Motifs conserved in helicase superfamily 2 are indicated in different colors and labeled. The red arrows indicate the positions of mutations.