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Recombinant Vesicular Stomatitis Virus Vaccine Vectors Expressing Filovirus Glycoproteins Lack Neurovirulence in Nonhuman Primates

Figure 1

Neurovirulence assay design.

(A) Illustration of the rVSV genomes used in the IT inoculation procedures. Note that the only difference between the rVSV vectors used in this study were the glycoproteins. (B) Schematic of the sampling days during the 21 day study. S = swab, B = blood, N = necropsy, * day 5 necropsy of 67-01, ** day 6 necropsy of 56-09.

Figure 1

doi: https://doi.org/10.1371/journal.pntd.0001567.g001