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The Genome of Mycobacterium Africanum West African 2 Reveals a Lineage-Specific Locus and Genome Erosion Common to the M. tuberculosis Complex

Figure 1

Position of GM041182 in the Mycobacterium tuberculosis complex genome phylogeny.

The phylogenetic tree is based on the mapping of Illumina data for representative strains of the complex to the newly generated M. africanum GM041182. The phylogeny was reconstructed using Neighbor-joining and is based on 9,699 variable positions in at least one strain. One thousand bootstrap pseudo-replicates were used to assess clade reliability. All nodes had more than 90% support. The positions of RD900h and RD900h are indicated. Numbers in branches refers to the corresponding number of SNPs inferred. Lineage names are according Hersbergh 2008 while numbers are according to Comas et al. 2010. A review of the nomenclature and comparison with other typing systems can be found in Coscolla and Gagneux 2010 [70] and Comas et al. 2009 [71].

Figure 1

doi: https://doi.org/10.1371/journal.pntd.0001552.g001