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Association of Mast Cell-Derived VEGF and Proteases in Dengue Shock Syndrome

Figure 2

Plasma levels of VEGF, sVEGFRs, tryptase, and chymase in Dengue patients during the admission period.

Plasma levels of VEGF, sVEGFR-1 and -2, tryptase, and chymase were examined for Dengue patients with DHF (A) and DSS (B) by ELISA. VEGF in DHF *p<0.01 (day 4 versus day 0 and 2) and DSS *p<0.01 (day 2 and 4 versus day 0), sVEGFR-1 in DSS *p<0.01 (day 2 and 4 versus day 0), sVEGFR-2 in DHF *p<0.01 (day 4 versus day 0 and 2) and DSS *p<0.01 (day 4 versus day 0 and 2), tryptase in DHF *p<0.01 (day 4 versus day 0 and 2) and DSS *p<0.01 (day 4 versus day 0 and 2), chymase in DSS *p<0.01 (day 4 versus day 0 and 2). Results are representative of two independent experiments.

Figure 2

doi: https://doi.org/10.1371/journal.pntd.0001505.g002