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Analysis of Salmonella enterica Serotype Paratyphi A Gene Expression in the Blood of Bacteremic Patients in Bangladesh

Figure 3

Quantitative-PCR mRNA expression profiles.

Quantitative-PCR mRNA expression profiles during in vitro and in vivo growth of S. Paratyphi A of genes associated with significantly different levels of detection in in vivo versus in vitro samples using SCOTS-array analysis. Quantitative RT-PCR gene profiles of S. Paratyphi A genes (A–E) comparing RNA recovered from blood of bacteremic patients to in vitro cultures, and a house-keeping gene with no differential expression by SCOTS-microarray analysis (F). Mean copies of mRNA per copy of 16S rRNA, standard error of the mean (SEM), and fold-induction (G) are presented. * p<0.05; † p<0.01; ‡ p<0.001.

Figure 3

doi: https://doi.org/10.1371/journal.pntd.0000908.g003