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Murine Models for Trypanosoma brucei gambiense Disease Progression—From Silent to Chronic Infections and Early Brain Tropism

Figure 2

Time course of total serum IgM levels in BALB/c mice infected with different T. b. gambiense field isolates.

Four mice were infected with either a low (103) or a high (106) load of Tbg945b, Tbg1122b, Tbg1135b or Tbg1135c isolates then IgM levels were quantified by ELISA test 1 month (black bars), 3 months (white bars), 5 months (gray bars) and 12 months (hatched bars) after infection. IgM levels are expressed as a multiple (mean±standard error) of the level before infection.

Figure 2

doi: https://doi.org/10.1371/journal.pntd.0000509.g002