Host Gene Expression Profiling of Dengue Virus Infection in Cell Lines and Patients
Figure 4
Culture supernatants of A549 and HepG2 cells infected with TSV01 (MOI 10) or heat-inactivated TSV-01 (HI-TSV01; MOI 10) for 72 hrs were analyzed for IP-10 (A) and I-TAC (B) by ELISA.
Results are expressed as mean±s.e.m. where n = 3–5. Significance (P<0.05) was determined by students t-test, comparing TSV01 to HI-TSV01 at each time point. Serum samples from dengue patients (n = 10) at first visit (1–2 days after fever onset), second visit (4–5 days after fever onset), convalescence and from non-dengue fever patients (n = 10) at the first visit (1–2 days after fever onset) were assayed for the presence of IP-10 (C) and I-TAC (D) by ELISA. Results are shown as a scatter plot with a bar indicating the mean.