Whole Blood Gene Expression Profiles to Assess Pathogenesis and Disease Severity in Infants with Respiratory Syncytial Virus Infection
Figure 1
Flow diagram of study patients.
Patient allocation and analyses performed throughout the study are depicted in Figure 1: RSV signature analysis (A), discrimination and modular analyses (B), follow-up analysis (C), age analyses (D), and disease severity analysis (E). Patients included in the different sub-analyses were matched for age, gender, and race/ethnicity with controls. In addition, for the age analyses (D), children greater or younger than 6 mo were matched for disease severity. Asterisk indicates that RSV patients used for viral discrimination analysis (B) were previously used in the RSV signature analysis (A). Ctrl, control; FU, follow-up.