Hyperinfectivity: A Critical Element in the Ability of V. cholerae to Cause Epidemics?
Figure 1
Models of Cholera Transmission
(A) Model of cholera transmission, neglecting a HI state of V. cholerae. Simple model reflecting a picture of contagion in which susceptibles (S) become infectious (I) after consuming concentrations (shown by B) of V. cholerae. Individuals may achieve a transient immunity (R) after recovery.
(B) Model of cholera transmission, incorporating a HI state of V. cholerae. This model includes contagion of V. cholerae that is HI (H) for a brief time after shedding and decays into a state of lower infectiousness (L). Greek letters denote rates of transitions between the different states, as described in Table 1.