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Gene Mutations in Lung Cancer: Promising Predictive Factors for the Success of Molecular Therapy

Figure 1

EGFR Signal Transduction in Cancer Cells

Arrows indicate stimulation, and T-bars, inhibition. EGFR-I, EGFR inhibitor; MEK, MAPK kinase.

doi: https://doi.org/10.1371/journal.pmed.0020013.g001