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Background Selection as Baseline for Nucleotide Variation across the Drosophila Genome

Figure 6

Relationship between estimates of B and π_sil.

(A) Relationship between estimates of B and π_sil for 100-kb autosomal regions. Spearman's ρ = 0.770 (1,189 regions, P<1×10⁻¹²). (B) Relationship between estimates of B and π_sil for 10-kb autosomal regions. Spearman's ρ = 0.678 (8,883 regions, P<1×10⁻¹²). Dark blue and red diamonds indicate regions with π_sil significantly different (higher or lower) than predicted based on residual analysis: dark blue (P<0.01), red (FDR-corrected q<0.10). Results shown for the default model M_{LN,StdMut,CO+GC}.

doi: https://doi.org/10.1371/journal.pgen.1004434.g006