Activating Transcription Factor 6 Is Necessary and Sufficient for Alcoholic Fatty Liver Disease in Zebrafish
Figure 3
Glyceroneogenesis and fatty acid elongation pathways are dysregulated by nAtf6 overexpression.
Schematic of the glycolysis, gluconeogenesis and glyceroneogenesis pathway (A, adapted from WikiPathways) and heatmap of associated genes (B). Upregulated genes are colored in shades of orange, downregulated genes are colored in shades of green, genes that are unchanged are white and those genes that did not appear in mRNA-Seq analyses are colored gray. Log values and median fold changes from mRNA-Seq analysis and qPCR, respectively, are noted.