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Comprehensive Methylome Characterization of Mycoplasma genitalium and Mycoplasma pneumoniae at Single-Base Resolution

Figure 3

Genome-wide distribution of 5′-GAN7TAY-3′/3′-CTN7ATR-5′ motif.

(A) Map of the genome of M. pneumoniae representing the enriched regions for the 5′-GAN7TAY-3′/3′-CTN7ATR-5′ motif. (B) Schematic representation of the cytadherence operon. The red square indicates the main “hot spot” of methylation for the Type I motif. (C) Upstream sequence of MPNs383. Red stars indicate the methylation by M.MpnI and blue stars indicate methylation by M.MpnII. The black arrow shows the transcriptional start site (TSS) of the MPNs383 and the red box the promoter sequence of this antisense RNA.

Figure 3

doi: https://doi.org/10.1371/journal.pgen.1003191.g003