A Novel Human-Infection-Derived Bacterium Provides Insights into the Evolutionary Origins of Mutualistic Insect–Bacterial Symbioses
Figure 2
Alignment between strain HS contigs (top) and chromosomes of SOPE (left) and S. glossinidius (right).
The draft strain HS contigs are depicted in an arbitrary color scheme (outer top ring). Contigs sharing <5 kb synteny with either the SOPE or S. glossinidius genome are uncolored. The uppermost plot (colored in purple and orange) depicts G+C skew, based on a 40 kb sliding window. For upper tracks, grey bars depict genes unique to strain HS whereas green bars depict strain HS genes that share orthologs with the aligned symbiont chromosome. For lower tracks, green and red bars represent (respectively) intact and disrupted orthologs of strain HS genes in the insect symbiont genomes, whereas blue bars highlight prophage and IS-element sequences in the insect symbiont chromosomes. Plots of pairwise nucleotide sequence identity are shown in the lower alignment following in silico removal of prophage and IS-elements from the SOPE and S. glossinidius sequences. Consensus oriC and dif sequences are labeled to indicate putative origins and termini of chromosome replication.