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Successive Increases in the Resistance of Drosophila to Viral Infection through a Transposon Insertion Followed by a Duplication

Figure 3

Mapping resistance using site-specific male-induced recombination.

Recombination was induced at the four positions shown in panel A to produce four recombinant lines (A, B, C and D). Relative gene locations in the 36 kb region are indicated [36]. The susceptibility of these lines to the sigma virus is shown in Panel B (green bars). There is a large difference in the susceptibility of recombinants C and D, suggesting that the causative gene is located in the region shown in the box. The infection rate of susceptible controls is shown in yellow and the resistant controls in blue. In crosses A and B we were unable to create any resistant controls, and are therefore unable to control for other genes in the genetic background of these stocks.

Figure 3

doi: https://doi.org/10.1371/journal.pgen.1002337.g003