Identification of Functional Toxin/Immunity Genes Linked to Contact-Dependent Growth Inhibition (CDI) and Rearrangement Hotspot (Rhs) Systems
Figure 2
Many bacteria contain orphan cdiA-CT/cdiI modules.
The cdi loci from selected bacterial species are presented using the color-coding scheme in Figure 1. Arrowheads indicate the positions of VENN encoding regions. Probable orphan cdiA-CT/cdiI modules are indicated with an “o” and numeral. Note the change in scale for the locus from E. coli EC869. The UniProt accession numbers for the encoded CdiA proteins are: Escherichia coli 254 ser. O113:H21 (A1XT91); Edwardsiella ictaluri 93–146 (C5BAK2); Erwinia pyrifoliae DSM 12163 (D2T668); Edwardsiella tarda EIB202 (D0ZDG0); Klebsiella variicola At-22 (D3RCW8); Neisseria menigitidis FAM18 (A1KSB8); Photorhabdus asymbiotica ATCC 43949 (B6VKN5); Pectobacterium wasabiae WPP163 (D0KFH4); Yersinia pseudotuberculosis PB1/+ (B2K3A8); and Escherichia coli EC869 (B3BM48). The E. coli 254 genomic sequence does not include the 5′-end of the cdiA gene.