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Stress-Induced PARP Activation Mediates Recruitment of Drosophila Mi-2 to Promote Heat Shock Gene Expression

Figure 8

Model.

Upon HS, PARylation of the locus creates binding sites for PAR-sensing regions of dMi-2. dMi-2 is recruited and, subsequently, interacts with nascent transcripts to support transcription and processing. GAF: GAGA Factor, HSE: HS elements.

Figure 8

doi: https://doi.org/10.1371/journal.pgen.1002206.g008