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Multiple Loci Are Associated with White Blood Cell Phenotypes

Figure 3

The directionality and magnitude of effects for SNPs significant in both the meta-analysis and eQTL analysis are highly correlated (r2 = 0.795).

Effect estimates in both the eQTL analysis and meta-analysis were standardized to effects based on dosages of the minor allele for each SNP. Meta-analysis effects are based on beta coefficients from regression, while eQTL effects are based on standardized betas. This figure only includes significant SNPs to improve clarity.

Figure 3

doi: https://doi.org/10.1371/journal.pgen.1002113.g003