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A Sustained Dietary Change Increases Epigenetic Variation in Isogenic Mice

Figure 1

Methylation levels are unchanged after methyl donor supplementation.

Whole-genome 5-methylcytosine (m5C) content in liver DNA from control, F1 supplemented (F1 Methyl) and F6 supplemented (F6 Methyl) mice as assessed by HPLC (n = 5 per group). Error bars indicate standard deviation.

Figure 1

doi: https://doi.org/10.1371/journal.pgen.1001380.g001