Comparative ICE Genomics: Insights into the Evolution of the SXT/R391 Family of ICEs
Figure 3
The boundaries of the 5 hotspots.
The boundaries between conserved and hotspot variable regions are shown. Black typeface indicates conserved sequence, while color indicates variable sequence. Numbers in parentheses indicate the number of intervening nucleotides. The thin dotted lines indicate continuations of variable DNA. Bold letters indicate a non-conserved base. (A) Hotspot 1, which is present between traJ and traL. Line 1: SXT, ICEVchInd4, ICEPalBan1; Line 2: R391, ICEPdaSpa1, ICEVchBan5, ICEVchInd5, ICEPmiUSA, ICESpuPO1, ICEVflInd, ICEVchMoz10, ICEVchBan9; Line 3: ICEVchMex1. (B) Hotspot 2, which is present between traA and s054. Line 1: SXT, ICEVchInd4, ICEPmiUSA, ICEVflInd, ICEVchInd5, ICEPalBan1, ICEVchBan5; Line 2: ICEPdaSpa1, ICEVchMoz10, ICEVchBan9; Line 3: R391; Line 4: ICEVchMex1; Line 5: ICESpuPO1. (C) Hotspot 3, which is present between s073 and traF. Line 1: SXT, ICEVchInd4; Line 2: ICEVchMex1, ICEVflInd; Line 3: ICEVchMoz10, ICEVchBan9, ICEVchInd5, ICEPalBan1, ICEVchBan5. Line 4: R391; Line 5: ICEPmiUSA; Line 6: ICESpuPO1; Line 7: ICEPdaSpa1. (D) Hotspot 4, which is present between traN and s063. Line 1: SXT, ICEVchInd4. Line 2: ICEVchInd5, ICEVchBan5; Line 3: ICESpuPO1, ICEPmiUSA; Line 4: R391, ICEVchMoz10, ICEVchBan9, ICEVflInd. Line 5: ICEPdaSpa1; Line 6: ICEPalBan1; Line 7: ICEVchMex1. (E) Hotspot 5, which is present between s026 and traI. Line 1: SXT, ICEVchInd4, ICEPdaSpa1, R391, ICEVchMoz10, ICEVchBan9; Line 2: ICEPmiUSA; Line 3: ICESpuPO1, ICEPalBan1, ICEVflInd1; Line 4: ICEVchInd5, ICEVchBan5; Line 5: ICEVchMex1.