Stage-Specific Expression Profiling of Drosophila Spermatogenesis Suggests that Meiotic Sex Chromosome Inactivation Drives Genomic Relocation of Testis-Expressed Genes
Figure 6
Mitotic and meiotic expression of individual parental-retrogene pairs.
(A) Pairs retroposed from X chromosome; (B) Pairs retroposed from autosomes. Differential gene intensity stands for a difference in expression intensities between meiosis and mitosis. Parental genes and retrogenes intensities (log2) are shown in blue and red dots, respectively. Solid lines connect mitosis and meiosis intensity averages of three replicates. The X-axis numbers correspond to parental-retrogene pairs ordered according to Table S2. The numbers on the top of each parental-retrogene segment (between green lines) correspond to the posterior Bayesian probabilities that a pair shows complementary expression (Model B in Statistical Analyses, Methods in Text S1). The bottom yeses (Y) indicate genes where those probabilities are above 50% (Statistical Analyses, Methods in Text S1). Most of X→A parental-retrogene pairs (A) show either a probability of zero or one for complementary expression, whereas several A→A parental-retrogene pairs (B) have probabilities that are markedly different from zero or one (e.g., 0.7 and 0.4). These uncertainties when classifying genes directly affects the confidence intervals, which are much larger for A→A than for X→A parental-retrogene pairs (Figure 5C).