Tor1/Sch9-Regulated Carbon Source Substitution Is as Effective as Calorie Restriction in Life Span Extension
Figure 7
Inhibition of the Tor1/Sch9 and Ras pathways activates stress response transcription factors and glycerol biosynthesis.
The metabolic changes in long lived mutants generate a calorie restriction-like environment, which contributes to enhanced stress resistance and extended life span.