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Genome-Wide Analysis of Factors Affecting Transcription Elongation and DNA Repair: A New Role for PAF and Ccr4-Not in Transcription-Coupled Repair

Figure 7

The increased UV sensitivity of PAF and Ccr4-Not mutants in the absence of global genome repair is not due to checkpoint activation failure.

(A) UV sensitivity curves of strains carrying single and double combinations of the rad9 or bre1, and rad7 mutations. (B) UV sensitivity curves of strains carrying single, double, and triple combinations of the rtf1, rad9, and rad7 mutations (left), the not5, rad9, and rad7 mutations (middle), or the rpb9, rad9, and rad7 mutations (right). Average values and standard deviations from at least 3 independent experiments are shown.

Figure 7

doi: https://doi.org/10.1371/journal.pgen.1000364.g007