A Screen for Suppressors of Gross Chromosomal Rearrangements Identifies a Conserved Role for PLP in Preventing DNA Lesions
Figure 3
Deletion of BUD16 Also Increases GCR Formation at ChrV-L
(A) GCR rate of either the wild-type (WT) or bud16Δ strain at ChrV-L.
(B) Whole-chromosome PFGE analysis of wild-type (W), parental bud16Δ (B), or bud16Δ strains that have undergone a GCR event (1–8). Left panel: ethidium bromide–stained gel. Right panel: Southern blot with a ChrV-specific probe (MCM3).