Anatomic Demarcation by Positional Variation in Fibroblast Gene Expression Programs
Figure 2
A Gene Expression Signature Divides Fibroblasts from Anterior and Posterior Sites of the Human Body
(A) Unsupervised hierarchical clustering separated fibroblasts from above and below the umbilicus. Blue bars indicate anterior (rostral) samples; green bars indicate posterior (caudal) samples.
(B) Supervised analysis with SAM using all samples identifies two distinct gene expression profiles corresponding to the origin of most samples being anterior and posterior to the umbilicus (FDR = 1%).