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Immersed Boundary Models for Quantifying Flow-Induced Mechanical Stimuli on Stem Cells Seeded on 3D Scaffolds in Perfusion Bioreactors

Fig 9

Shear stress (τ) on the cell surface due to imposed flow for distinct configurations (A, F, T and B) of cells on scaffold struts.

Left: color maps showing local shear stress. The arrows indicate the direction of the flow; scale bar 10 μm. Top right: distribution of shear stress for A, F, T, B. Bottom right: mean shear stress (dark color) and maximal shear stress (light color) for cases A, F, T and B. The empty bars indicate the shear stress on the empty scaffold strut at the cell’s location (computed at the macro-scale).

Fig 9

doi: https://doi.org/10.1371/journal.pcbi.1005108.g009