Immersed Boundary Models for Quantifying Flow-Induced Mechanical Stimuli on Stem Cells Seeded on 3D Scaffolds in Perfusion Bioreactors
Fig 3
Determination of cell stiffness by means of micropipette aspiration.
Left: Visualization of simulated micropipette aspiration experiment. Right: Equilibrium Young’s Modulus E∞ as a function of stretching stiffness ks for varying cortical thickness tc. For the parameter values extracted from the AFM measurements, an equilibrium Young’s modulus of 194.7 Pa was obtained.