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Brain Connectivity Dissociates Responsiveness from Drug Exposure during Propofol-Induced Transitions of Consciousness

Fig 4

Alpha band connectivity networks.

Network topographs are visualised at each level of sedation, averaged over participants in the responsive (A) and drowsy (B) groups. Colour of the scalp indicates the degree of a node. The normalised height of an arc connecting two nodes indicates the strength of the dwPLI link between them. Network modules were identified by the Louvain algorithm. For visual clarity, of the strongest 30% of links, only the intra-modular links are plotted. The colour of an arc identifies the module to which it belongs. While alpha band networks in the responsive group exhibited a relatively stable fronto-centro-occipital pattern of connectivity, the drowsy group altered significantly, and registered a pronounced frontally centered module during moderate sedation.

Fig 4

doi: https://doi.org/10.1371/journal.pcbi.1004669.g004