Genome-Wide Detection and Analysis of Multifunctional Genes
Fig 5
Multifunctional genes are involved in a significantly larger number of regulatory and genetic interactions.
Boxplots of the number of regulatory and/or genetic interactions for multifunctional and other annotated genes are shown for (A) fly, (B) human, and (C) yeast. Colored dots show the means, notches show bootstrap-generated 95% confidence intervals around the medians, boxes show quartile ranges, and whiskers extend to the most extreme data points within 1.5 times the size of the inner quartile range. Multifunctional genes are involved in significantly more regulatory and genetic interactions (Mann–Whitney U test).