Within-Host Stochastic Emergence Dynamics of Immune-Escape Mutants
Fig 5
Comparing pathogen growth against death rate.
3D plot comparing the emergence probability if the death rate σ is reduced by a factor 1/c = 1.01 (here denoted Pσ), to the case where the growth rate φ is increased by c = 1.01 (denoted Pφ). Plot (A) is for the case where immune response dy / dx = ρxy(1 − y/K), as in our model, and (B) assumes dy / dx = ρφxy(1 − y/K) to enable comparison of our model with [27]. Other parameters are K = 1,000, R = 100, xinit = 1, yinit = 20, μ = 0.025 and σ1 = 1 for (B).