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HPV Clearance and the Neglected Role of Stochasticity

Fig 2

Replacement dynamics.

(A) T-cell elimination of an infected daughter cell (D*) triggers division of an S or S* cell with probabilities ps and ps*, respectively. The division event is identical to spontaneous division in Fig. 1B. (B) T-cell elimination of an infected stem cell S* triggers division of an S or S* cell. However, as required by homeostatic equilibrium of the stem cell compartment (on average), the division is assumed to yield two identical stem cells, see text for details.

Fig 2

doi: https://doi.org/10.1371/journal.pcbi.1004113.g002